The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Isoleucyl-tRNA Synthetase; Domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14397: Putative leucine--tRNA ligase, cytoplasmic

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Leucine--tRNA ligase. [EC: 6.1.1.4]
ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).
    748 A0A031LKH0 A0A031LKH0 A0A031LV60 A0A031LV60 A0A060HQ85 A0A060HQ85 A0A060T503 A0A060T503 A0A062V9W3 A0A062V9W3
    (738 more...)
    Valine--tRNA ligase. [EC: 6.1.1.9]
    ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val).
      10 A6US78 A6US78 A6UVK1 A6UVK1 D7DTX5 D7DTX5 F8AKC5 F8AKC5 N6UVX9 N6UVX9
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