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CATH Superfamily 1.10.10.2530

Pre-mRNA-splicing helicase BRR2-like; Chain B, domain 9

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Pre-mRNA-splicing helicase BRR2-like; Chain B, domain 9

The name has been chosen based on PDBs with domains in this superfamily since all the given structures correspond to domain 9 in chain B of the RNA helicase BRR2. This is backed up by the EC and GO entries which highlight the helicase activity of the members of this superfamily. It is important to note that, when considering UniProt-SwissProt entries, both DNA (activating signal cointegrator 1 complex subunit 3) and RNA helicase (BRR2) activity is reported for this superfamily. However, as already shown, the available structural information has been the main determinant for naming this superfamily.

GO Diversity

Unique GO annotations
53 Unique GO terms

EC Diversity

Unique EC annotations
10 Unique EC terms

Species Diversity

Unique species annotations
1406 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 10
Domain clusters (>95% seq id): 4
Domain clusters (>35% seq id): 2
Unique PDBs: 5
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC: 10
Unique GO: 53
Taxonomy
Unique Species: 1406