View in Gene3D

CATH Superfamily 1.10.10.1290

Transcriptional regulator DELLA, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Transcriptional regulator DELLA, N-terminal domain

Gibberellins (GAs) are widely known as endogenous hormones in plants, which have great impact on growth signalling. This superfamily represents the N-terminal domain of DELLA protein, transcriptional regulators of growth related proteins which are downregulated when gibberellins bind to their receptor GID1 (Gibberellin Insensitive Dwarf 1). GID1 forms a complex with DELLA proteins and signals them towards 26S proteasome. The N-terminal of DELLA proteins contains conserved DELLA and VHYNP motifs which are important for GID1 binding and proteolysis of the DELLA proteins PMID:19037309.

PFAM:PF12041,INTERPRO:IPR021914

GO Diversity

Unique GO annotations
23 Unique GO terms

EC Diversity

Unique EC annotations
2 Unique EC terms

Species Diversity

Unique species annotations
443 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 2
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 2
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC: 2
Unique GO: 23
Taxonomy
Unique Species: 443