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CATH Superfamily 1.10.10.1250

RNA polymerase, subunit delta, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: RNA polymerase, subunit delta, N-terminal domain

RNA polymerase (RNAP) is a multi-subunit enzyme with a high level of homology across several bacterial species, although there are significant differences in the number of subunits and the amino acid sequence. The delta subunit of RNAP consists of two domains: N-terminal (ordered structure) and C-terminal (unordered and flexible). The delta subunit was shown to be involved in the regulation of transcription initiation and in the adaptation to changes in the environment. This superfamily entry represents the N-terminal domain of the delta subunit PMID:24937760,PMID:20310067,PMID:23868186.

PFAM:PF05066,INTERPRO:IPR007759

GO Diversity

Unique GO annotations
1 Unique GO terms

EC Diversity

Unique EC annotations
5 Unique EC terms

Species Diversity

Unique species annotations
2739 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 6
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 4
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC: 5
Unique GO: 1
Taxonomy
Unique Species: 2739