The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 98765: Histone acetyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histone acetyltransferase activity (H3-K23 specific) GO:0043994
Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23).
1 Q9W1A9 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuroblast proliferation GO:0007405
The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.
1 Q9W1A9 (/IMP)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
1 Q9W1A9 (/IMP)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
1 Q9W1A9 (/IMP)
Dorsal/ventral axon guidance GO:0033563
The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
1 Q9W1A9 (/IMP)
Female germ-line stem cell population maintenance GO:0036099
The process by which an organism or tissue maintains a population of female germ-line stem cells.
1 Q9W1A9 (/IMP)
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
1 Q9W1A9 (/IDA)
Regulation of JAK-STAT cascade GO:0046425
Any process that modulates the frequency, rate or extent of the JAK-STAT signaling pathway.
1 Q9W1A9 (/IMP)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 Q9W1A9 (/IDA)
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
1 Q9W1A9 (/IGI)
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
1 Q9W1A9 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MOZ/MORF histone acetyltransferase complex GO:0070776
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
1 Q9W1A9 (/IDA)