The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 266283: Lysine-specific histone demethylase 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
L-amino-acid oxidase. [EC: 1.4.3.2]
An L-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).
    4 B9SUY7 B9SUY7 B9T642 B9T642
    Transferred entry: 1.5.3.13, 1.5.3.14, 1.5.3.15, 1.5.3.16 and 1.5.3.17. [EC: 1.5.3.11]
      4 B7PJ47 B7PJ47 B7PX42 B7PX42
      Monoamine oxidase. [EC: 1.4.3.4]
      RCH(2)NHR' + H(2)O + O(2) = RCHO + R'NH(2) + H(2)O(2).
      • Catalyzes the oxidative deamination of neurotransmitters and biogenic amines.
      • Acts on primary amines, and also on some secondary and tertiary amines.
      • It differs from EC 1.4.3.21, as it can oxidize secondary and tertiary amines but not methylamine.
      • Inhibited by acetylenic compounds such as chlorgyline, 1-deprenyl and pargyline but, unlike EC 1.4.3.21 and EC 1.4.3.22, it is not inhibited by semicarbazide.
      • Formerly EC 1.4.3.9.
      2 B7PX42 B7PX42