The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 265134: LysR family transcriptional regulator

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding GO:0001131
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase in order to modulate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 P0A9F6 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q9KTK6 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 P24734 (/IDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 P0A9F6 (/IDA) P24734 (/IDA)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 P0A9F6 (/IDA)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 P0A9F6 (/IEP)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 P0A9F6 (/ISS)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9KTK6 (/ISS)
Positive regulation of proteolysis GO:0045862
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
1 P24734 (/IMP)
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
1 P24734 (/IMP)
Negative regulation of single-species biofilm formation on inanimate substrate GO:1900232
Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
1 P24734 (/IMP)
Positive regulation of secondary metabolite biosynthetic process GO:1900378
Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.
1 P24734 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
1 P24734 (/IDA)