CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 264789: Forkhead box subgroup O
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 53 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
15 |
A0A096MJF0 (/IPI)
A8MYZ6 (/IPI)
D4A433 (/IPI)
F1QVZ3 (/IPI)
O16850 (/IPI)
O43524 (/IPI)
P98177 (/IPI)
Q12778 (/IPI)
Q5TYS1 (/IPI)
Q95V55 (/IPI)
(5 more) |
|
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
12 |
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
B4PTD3 (/ISS)
B4R0I7 (/ISS)
(2 more) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
8 | G3V7R4 (/IDA) O16850 (/IDA) O43524 (/IDA) Q12778 (/IDA) Q95V55 (/IDA) Q9R1E0 (/IDA) Q9WVH3 (/IDA) Q9WVH4 (/IDA) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
8 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q66JJ0 (/ISS) Q6EUW1 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
7 | G3V7R4 (/IDA) O16850 (/IDA) O43524 (/IDA) P98177 (/IDA) Q95V55 (/IDA) Q9R1E0 (/IDA) Q9WVH4 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
5 | O43524 (/IDA) P98177 (/IDA) Q95V55 (/IDA) Q9R1E0 (/IDA) Q9WVH4 (/IDA) |
|
Protein phosphatase 2A binding GO:0051721
Interacting selectively and non-covalently with the enzyme protein phosphatase 2A.
|
5 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q12778 (/ISS) Q810W5 (/ISS) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
4 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) |
|
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
3 | Q9R1E0 (/ISO) Q9WVH3 (/ISO) Q9WVH4 (/ISO) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
3 | Q9R1E0 (/ISO) Q9WVH3 (/ISO) Q9WVH4 (/ISO) |
|
RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0000981
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
2 | B3G3K1 (/IDA) Q70KY4 (/IDA) |
|
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
2 | O43524 (/ISS) Q6EUW1 (/ISS) |
|
Transcription cofactor binding GO:0001221
Interacting selectively and non-covalently with a transcription cofactor, any protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
|
2 | A0A096MJN1 (/IPI) D3ZBQ1 (/IPI) |
|
Transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001227
Interacting selectively and non-covalently with a sequence of DNA that is in the regulatory region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q9R1E0 (/IGI) Q9WVH4 (/IGI) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | Q9WVH3 (/ISO) Q9WVH4 (/ISO) |
|
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
2 | Q9WVH3 (/ISO) Q9WVH4 (/ISO) |
|
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
2 | P98177 (/IDA) Q12778 (/IDA) |
|
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
2 | O16850 (/IPI) O43524 (/IPI) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
2 | P98177 (/IPI) Q9R1E0 (/IPI) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
2 | O16850 (/IPI) P98177 (/IPI) |
|
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
|
2 | Q95V55 (/IDA) Q9WVH4 (/IDA) |
|
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
|
2 | O43524 (/ISS) Q6EUW1 (/ISS) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
2 | O16850 (/IPI) Q12778 (/IPI) |
|
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
|
2 | A0A096MJF0 (/IDA) D4A433 (/IDA) |
|
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
|
1 | O16850 (/IDA) |
|
RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0000981
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | A8MYZ6 (/ISS) |
|
Transcription factor activity, transcription factor binding GO:0000989
Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
|
1 | Q9R1E0 (/IPI) |
|
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | Q9WVH4 (/IDA) |
|
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
1 | Q95V55 (/IDA) |
|
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
1 | Q95V55 (/IMP) |
|
Transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001078
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q9R1E0 (/IDA) |
|
Transcription coactivator binding GO:0001223
Interacting selectively and non-covalently with a transcription coactivator, any protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
1 | G3V7R4 (/IPI) |
|
Transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001227
Interacting selectively and non-covalently with a sequence of DNA that is in the regulatory region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O43524 (/IDA) |
|
Transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001227
Interacting selectively and non-covalently with a sequence of DNA that is in the regulatory region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q9WVH4 (/ISO) |
|
Transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228
Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
1 | Q9WVH4 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q9WVH3 (/ISS) |
|
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | Q95V55 (/IMP) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | Q9WVH3 (/ISO) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | Q9WVH3 (/ISS) |
|
DEAD/H-box RNA helicase binding GO:0017151
Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase.
|
1 | O16850 (/IPI) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q9WVH3 (/ISO) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q9WVH3 (/ISS) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | O43524 (/IPI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q9WVH4 (/ISO) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q6EUW1 (/ISS) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q9R1E0 (/ISO) |
|
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
|
1 | O16850 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P98177 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q9WVH3 (/ISO) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | P98177 (/IMP) |
|
Protein phosphatase 2A binding GO:0051721
Interacting selectively and non-covalently with the enzyme protein phosphatase 2A.
|
1 | Q9R1E0 (/IDA) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | O16850 (/IPI) |
|
Ubiquitin-specific protease binding GO:1990381
Interacting selectively and non-covalently with a ubiquitin-specific protease.
|
1 | O16850 (/IPI) |
There are 235 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
12 |
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
B4PTD3 (/ISS)
B4R0I7 (/ISS)
(2 more) |
|
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
12 |
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
B4PTD3 (/ISS)
B4R0I7 (/ISS)
(2 more) |
|
Multicellular organism aging GO:0010259
An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).
|
11 |
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
B4PTD3 (/ISS)
B4R0I7 (/ISS)
(1 more) |
|
Regulation of lipid metabolic process GO:0019216
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
|
11 |
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
B4PTD3 (/ISS)
B4R0I7 (/ISS)
(1 more) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
11 |
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
B4PTD3 (/ISS)
B4R0I7 (/ISS)
(1 more) |
|
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
|
11 |
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
B4PTD3 (/ISS)
B4R0I7 (/ISS)
(1 more) |
|
Negative regulation of insulin receptor signaling pathway GO:0046627
Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.
|
11 |
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
B4PTD3 (/ISS)
B4R0I7 (/ISS)
(1 more) |
|
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
8 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
7 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
7 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) O43524 (/ISS) Q12778 (/ISS) Q6EUW1 (/ISS) Q810W5 (/ISS) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
7 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
7 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | B3G3K1 (/IDA) G3V7R4 (/IDA) O43524 (/IDA) Q12778 (/IDA) Q95V55 (/IDA) Q9WVH3 (/IDA) Q9WVH4 (/IDA) |
|
Cellular response to hyperoxia GO:0071455
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
|
7 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
6 | B3G3K1 (/IDA) O16850 (/IDA) O43524 (/IDA) P98177 (/IDA) Q12778 (/IDA) Q95V55 (/IDA) |
|
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
5 | F1QVZ3 (/IDA) O43524 (/IDA) Q5TYS1 (/IDA) Q9PVK6 (/IDA) Q9W7F8 (/IDA) |
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
5 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q12778 (/ISS) Q810W5 (/ISS) |
|
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
|
5 | E1BPQ1 (/ISS) G3V7R4 (/ISS) Q12778 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | Q66JJ0 (/ISS) Q6EUW1 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
5 | Q66JJ0 (/ISS) Q6EUW1 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Cellular response to nitric oxide GO:0071732
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
|
5 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q12778 (/ISS) Q810W5 (/ISS) |
|
Temperature homeostasis GO:0001659
A homeostatic process in which an organism modulates its internal body temperature.
|
4 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) |
|
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
4 | F1QVZ3 (/IMP) Q5TYS1 (/IMP) Q9PVK6 (/IMP) Q9W7F8 (/IMP) |
|
Cellular glucose homeostasis GO:0001678
A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment.
|
4 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | O16850 (/IDA) P98177 (/IDA) Q9R1E0 (/IDA) Q9WVH4 (/IDA) |
|
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
|
4 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) |
|
Negative regulation of Wnt signaling pathway GO:0030178
Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
|
4 | F1QVZ3 (/IGI) Q5TYS1 (/IGI) Q9PVK6 (/IGI) Q9W7F8 (/IGI) |
|
Negative regulation of Wnt signaling pathway GO:0030178
Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
|
4 | F1QVZ3 (/IPI) Q5TYS1 (/IPI) Q9PVK6 (/IPI) Q9W7F8 (/IPI) |
|
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
|
4 | A0A096MJF0 (/IEP) A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) D4A433 (/IEP) |
|
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
4 | A4L7N3 (/ISS) E1BPQ1 (/ISS) G3V7R4 (/ISS) Q12778 (/ISS) |
|
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
4 | F1QVZ3 (/IMP) Q5TYS1 (/IMP) Q9PVK6 (/IMP) Q9W7F8 (/IMP) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
4 | Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9R1E0 (/ISS) |
|
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
4 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
4 | O16850 (/IMP) Q95V55 (/IMP) Q9R1E0 (/IMP) Q9WVH4 (/IMP) |
|
Primitive hemopoiesis GO:0060215
A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
|
4 | F1QVZ3 (/IGI) Q5TYS1 (/IGI) Q9PVK6 (/IGI) Q9W7F8 (/IGI) |
|
Cellular response to cold GO:0070417
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
4 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) |
|
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
4 | F1QVZ3 (/IDA) Q5TYS1 (/IDA) Q9PVK6 (/IDA) Q9W7F8 (/IDA) |
|
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
4 | F1QVZ3 (/IMP) Q5TYS1 (/IMP) Q9PVK6 (/IMP) Q9W7F8 (/IMP) |
|
Response to water-immersion restraint stress GO:1990785
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile.
|
4 | A0A096MJF0 (/IEP) A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) D4A433 (/IEP) |
|
Regulation of energy homeostasis GO:2000505
Any process that modulates the frequency, rate or extent of energy homeostasis.
|
4 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) |
|
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | A8MYZ6 (/ISS) O43524 (/ISS) Q6EUW1 (/ISS) |
|
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
3 | A0A096MJN1 (/IDA) D3ZBQ1 (/IDA) O16850 (/IDA) |
|
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
3 | A4L7N3 (/IDA) O16850 (/IDA) P98177 (/IDA) |
|
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
3 | Q12778 (/ISS) Q810W5 (/ISS) Q9WVH3 (/ISS) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | Q9R1E0 (/ISO) Q9WVH3 (/ISO) Q9WVH4 (/ISO) |
|
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | O16850 (/IMP) O43524 (/IMP) |
|
Lymph vessel development GO:0001945
The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
|
2 | A3RK74 (/IGI) A3RK75 (/IGI) |
|
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | G3V7R4 (/IDA) Q9WVH4 (/IDA) |
|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
2 | A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) |
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
2 | O16850 (/IDA) Q9R1E0 (/IDA) |
|
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
2 | A0A096MJF0 (/IEP) D4A433 (/IEP) |
|
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
2 | P98177 (/IDA) Q9WVH3 (/IDA) |
|
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
2 | O16850 (/IGI) Q95V55 (/IGI) |
|
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
2 | O16850 (/IMP) Q95V55 (/IMP) |
|
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | A4L7N3 (/IMP) F1RME6 (/IMP) |
|
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
|
2 | A0A096MJF0 (/IMP) D4A433 (/IMP) |
|
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
|
2 | A4L7N3 (/IDA) F1RME6 (/IDA) |
|
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
|
2 | A4L7N3 (/IDA) F1RME6 (/IDA) |
|
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
2 | B3G3K1 (/IDA) Q9R1E0 (/IDA) |
|
Tumor necrosis factor-mediated signaling pathway GO:0033209
A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q6EUW1 (/ISS) Q9WVH4 (/ISS) |
|
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
2 | Q9R1E0 (/IDA) Q9WVH4 (/IDA) |
|
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
2 | O16850 (/IGI) Q9WVH4 (/IGI) |
|
Negative regulation of multicellular organism growth GO:0040015
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.
|
2 | O16850 (/IMP) Q95V55 (/IMP) |
|
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
2 | A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) |
|
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
|
2 | Q95V55 (/IMP) Q9WVH4 (/IMP) |
|
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
2 | O16850 (/IMP) Q95V55 (/IMP) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
2 | O16850 (/IMP) Q12778 (/IMP) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
2 | Q9R1E0 (/ISO) Q9WVH4 (/ISO) |
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
2 | A0A096MJN1 (/IMP) D3ZBQ1 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q9R1E0 (/ISO) Q9WVH4 (/ISO) |
|
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
|
2 | A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) |
|
Cellular response to corticosterone stimulus GO:0071386
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
|
2 | A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) |
|
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
2 | A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) |
|
Response to dexamethasone GO:0071548
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
|
2 | A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) |
|
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
2 | Q9R1E0 (/IGI) Q9WVH4 (/IGI) |
|
Neuronal stem cell population maintenance GO:0097150
Any process in by an organism or tissue maintains a population of neuronal stem cells.
|
2 | Q9R1E0 (/IGI) Q9WVH4 (/IGI) |
|
Positive regulation of hydrogen peroxide-mediated programmed cell death GO:1901300
Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.
|
2 | A0A096MJN1 (/IMP) D3ZBQ1 (/IMP) |
|
Positive regulation of reactive oxygen species biosynthetic process GO:1903428
Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.
|
2 | A0A096MJN1 (/IMP) D3ZBQ1 (/IMP) |
|
Positive regulation of complement-dependent cytotoxicity GO:1903661
Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity.
|
2 | A4L7N3 (/IMP) F1RME6 (/IMP) |
|
Cellular response to beta-amyloid GO:1904646
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-amyloid stimulus.
|
2 | A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) |
|
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
|
2 | A0A096MJN1 (/IEP) D3ZBQ1 (/IEP) |
|
Regulation of neural precursor cell proliferation GO:2000177
Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.
|
2 | Q9R1E0 (/IGI) Q9WVH4 (/IGI) |
|
Positive regulation of endothelial cell apoptotic process GO:2000353
Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.
|
2 | A0A096MJN1 (/IMP) D3ZBQ1 (/IMP) |
|
Regulation of reactive oxygen species metabolic process GO:2000377
Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.
|
2 | Q9R1E0 (/IGI) Q9WVH4 (/IGI) |
|
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q9WVH4 (/ISO) |
|
Ovulation from ovarian follicle GO:0001542
The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus.
|
1 | Q9WVH4 (/IMP) |
|
Initiation of primordial ovarian follicle growth GO:0001544
Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle).
|
1 | Q9WVH4 (/IMP) |
|
Antral ovarian follicle growth GO:0001547
Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.
|
1 | Q9WVH4 (/IMP) |
|
Oocyte maturation GO:0001556
A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
|
1 | Q9WVH4 (/IMP) |
|
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
|
1 | Q95V55 (/IMP) |
|
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
1 | Q9R1E0 (/IMP) |
|
Microtubule bundle formation GO:0001578
A process that results in a parallel arrangement of microtubules.
|
1 | Q95V55 (/IDA) |
|
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
|
1 | Q95V55 (/IMP) |
|
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
|
1 | O16850 (/IMP) |
|
Positive regulation of adaptive immune response GO:0002821
Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.
|
1 | O16850 (/IMP) |
|
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
|
1 | Q95V55 (/IMP) |
|
CAMP biosynthetic process GO:0006171
The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
|
1 | Q95V55 (/IDA) |
|
CAMP biosynthetic process GO:0006171
The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
|
1 | Q95V55 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q95V55 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9WVH3 (/ISO) |
|
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q70KY4 (/IMP) |
|
Transcription from RNA polymerase II promoter GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
1 | P98177 (/TAS) |
|
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
|
1 | O43524 (/IDA) |
|
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
|
1 | Q9WVH4 (/ISO) |
|
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
|
1 | Q9WVH4 (/ISS) |
|
Ecdysone biosynthetic process GO:0006697
The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
|
1 | Q95V55 (/IMP) |
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | Q95V55 (/IMP) |
|
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
1 | O16850 (/IGI) |
|
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
1 | Q95V55 (/IMP) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
1 | P98177 (/IDA) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
1 | Q9WVH3 (/ISO) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
1 | Q9WVH3 (/ISS) |
|
Mitotic G2 DNA damage checkpoint GO:0007095
A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
|
1 | Q9WVH3 (/IDA) |
|
Myoblast fusion GO:0007520
A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
1 | Q95V55 (/IMP) |
|
Somatic muscle development GO:0007525
The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.
|
1 | Q95V55 (/IMP) |
|
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
1 | O16850 (/IMP) |
|
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
|
1 | Q70KY4 (/IMP) |
|
Short-term memory GO:0007614
The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
|
1 | O16850 (/IGI) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | Q95V55 (/IMP) |
|
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q95V55 (/IMP) |
|
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q9WVH3 (/ISO) |
|
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | Q95V55 (/IGI) |
|
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | Q9R1E0 (/IMP) |
|
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | Q95V55 (/IPI) |
|
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | Q9WVH3 (/ISO) |
|
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | O16850 (/TAS) |
|
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
1 | O16850 (/IDA) |
|
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
|
1 | O16850 (/IGI) |
|
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
1 | Q12778 (/IDA) |
|
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
1 | Q95V55 (/IMP) |
|
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
1 | Q9R1E0 (/ISO) |
|
Response to UV GO:0009411
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
|
1 | O16850 (/IDA) |
|
Response to UV GO:0009411
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
|
1 | O16850 (/IGI) |
|
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
|
1 | Q95V55 (/IDA) |
|
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
|
1 | Q95V55 (/IMP) |
|
Multicellular organism aging GO:0010259
An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).
|
1 | Q95V55 (/IMP) |
|
Heat acclimation GO:0010286
Any process that increases heat tolerance of an organism in response to high temperatures.
|
1 | O16850 (/IGI) |
|
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | O16850 (/IGI) |
|
Regulation of autophagy GO:0010506
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q95V55 (/IMP) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q12778 (/IMP) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q9R1E0 (/ISO) |
|
Regulation of cell cycle process GO:0010564
Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
|
1 | O16850 (/IEP) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | O16850 (/IMP) |
|
Regulation of lipid storage GO:0010883
Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
|
1 | O16850 (/IGI) |
|
Negative regulation of lipid storage GO:0010888
Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
|
1 | Q95V55 (/IDA) |
|
Regulation of macroautophagy GO:0016241
Any process that modulates the frequency, rate or extent of macroautophagy.
|
1 | Q95V55 (/IMP) |
|
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
1 | P98177 (/IDA) |
|
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
1 | Q9WVH3 (/ISO) |
|
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
1 | Q9WVH3 (/ISS) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | P98177 (/TAS) |
|
Regulation of lipid metabolic process GO:0019216
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
|
1 | Q95V55 (/IMP) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
1 | Q95V55 (/IMP) |
|
DNA damage response, signal transduction by p53 class mediator GO:0030330
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
|
1 | Q9WVH4 (/IDA) |
|
Endocrine pancreas development GO:0031018
The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.
|
1 | Q12778 (/TAS) |
|
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
1 | G3V7R4 (/IEP) |
|
Negative regulation of stress-activated MAPK cascade GO:0032873
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
|
1 | Q12778 (/IDA) |
|
Negative regulation of stress-activated MAPK cascade GO:0032873
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
|
1 | Q9R1E0 (/ISO) |
|
Regulation of activin receptor signaling pathway GO:0032925
Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.
|
1 | Q95V55 (/IMP) |
|
Tumor necrosis factor-mediated signaling pathway GO:0033209
A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | O43524 (/IMP) |
|
Tumor necrosis factor-mediated signaling pathway GO:0033209
A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q9WVH4 (/ISO) |
|
Cellular response to amino acid starvation GO:0034198
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
|
1 | Q95V55 (/IDA) |
|
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
1 | Q95V55 (/IMP) |
|
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | O16850 (/IDA) |
|
Regulation of hemocyte proliferation GO:0035206
Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.
|
1 | Q95V55 (/IMP) |
|
Regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter GO:0035947
Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter.
|
1 | Q9R1E0 (/IMP) |
|
Female germ-line stem cell population maintenance GO:0036099
The process by which an organism or tissue maintains a population of female germ-line stem cells.
|
1 | Q95V55 (/IMP) |
|
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
|
1 | Q95V55 (/IGI) |
|
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
|
1 | Q95V55 (/IMP) |
|
Dauer larval development GO:0040024
The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
|
1 | O16850 (/IGI) |
|
Regulation of cell proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
1 | Q9R1E0 (/IMP) |
|
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
|
1 | Q9R1E0 (/IDA) |
|
Dauer exit GO:0043054
Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development.
|
1 | B3G3K1 (/IGI) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | O43524 (/IDA) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q12778 (/IDA) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q9R1E0 (/ISO) |
|
Regulation of neuron apoptotic process GO:0043523
Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.
|
1 | Q5I0F7 (/IMP) |
|
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
|
1 | O43524 (/IMP) |
|
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
|
1 | Q9WVH4 (/ISO) |
|
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
|
1 | Q6EUW1 (/ISS) |
|
Regulation of DNA-templated transcription in response to stress GO:0043620
Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
|
1 | O16850 (/IMP) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
1 | O16850 (/IMP) |
|
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
|
1 | Q95V55 (/IGI) |
|
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
|
1 | A4L7N3 (/IDA) |
|
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
|
1 | Q9R1E0 (/IMP) |
|
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
|
1 | O43524 (/IDA) |
|
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
|
1 | Q9WVH4 (/ISO) |
|
Positive regulation of gluconeogenesis GO:0045722
Any process that activates or increases the frequency, rate or extent of gluconeogenesis.
|
1 | Q9R1E0 (/IMP) |
|
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q12778 (/IMP) |
|
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q9R1E0 (/ISO) |
|
Negative regulation of cell size GO:0045792
Any process that reduces cell size.
|
1 | Q95V55 (/IMP) |
|
Positive regulation of synaptic growth at neuromuscular junction GO:0045887
Any process that activates or increases the frequency, rate or extent of synaptic growth at neuromuscular junction.
|
1 | O16850 (/IGI) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q95V55 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q95V55 (/IMP) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q9R1E0 (/IGI) |
|
Regulation of organ growth GO:0046620
Any process that modulates the frequency, rate or extent of growth of an organ of an organism.
|
1 | Q95V55 (/IMP) |
|
Regulation of insulin receptor signaling pathway GO:0046626
Any process that modulates the frequency, rate or extent of insulin receptor signaling.
|
1 | Q95V55 (/IGI) |
|
Negative regulation of insulin receptor signaling pathway GO:0046627
Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.
|
1 | Q95V55 (/IMP) |
|
Regulation of lipid biosynthetic process GO:0046890
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
|
1 | O16850 (/IMP) |
|
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell.
|
1 | Q95V55 (/IMP) |
|
Brain morphogenesis GO:0048854
The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | Q9WVH4 (/IGI) |
|
Stem cell differentiation GO:0048863
The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
1 | P98177 (/IMP) |
|
Stem cell differentiation GO:0048863
The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
1 | Q9WVH3 (/ISO) |
|
Stem cell differentiation GO:0048863
The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
1 | Q9WVH3 (/ISS) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
1 | O16850 (/IMP) |
|
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
|
1 | O16850 (/IMP) |
|
Negative regulation of smooth muscle cell differentiation GO:0051151
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
|
1 | P98177 (/IDA) |
|
Negative regulation of smooth muscle cell differentiation GO:0051151
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
|
1 | Q9WVH3 (/ISO) |
|
Negative regulation of smooth muscle cell differentiation GO:0051151
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
|
1 | Q9WVH3 (/ISS) |
|
Regulation of nervous system development GO:0051960
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
|
1 | Q5I0F7 (/IMP) |
|
Muscle tissue development GO:0060537
The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.
|
1 | O16850 (/IMP) |
|
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
1 | Q70KY4 (/IMP) |
|
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
1 | A8MYZ6 (/ISS) |
|
Regulation of dauer larval development GO:0061065
Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
|
1 | O16850 (/IGI) |
|
Positive regulation of dauer larval development GO:0061066
Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
|
1 | O16850 (/IMP) |
|
Enamel mineralization GO:0070166
The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.
|
1 | G3V7R4 (/IEP) |
|
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
1 | G3V7R4 (/IEP) |
|
Negative regulation of G0 to G1 transition GO:0070317
A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.
|
1 | P98177 (/IDA) |
|
Negative regulation of G0 to G1 transition GO:0070317
A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.
|
1 | Q9WVH3 (/ISO) |
|
Negative regulation of G0 to G1 transition GO:0070317
A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.
|
1 | Q9WVH3 (/ISS) |
|
Positive regulation of cell cycle arrest GO:0071158
Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.
|
1 | P98177 (/IDA) |
|
Positive regulation of cell cycle arrest GO:0071158
Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.
|
1 | Q9WVH3 (/ISO) |
|
Cellular response to hyperoxia GO:0071455
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
|
1 | Q12778 (/IDA) |
|
Cellular response to hyperoxia GO:0071455
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
|
1 | Q9R1E0 (/ISO) |
|
Cellular response to dexamethasone stimulus GO:0071549
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
|
1 | G3V7R4 (/IEP) |
|
Cellular response to nitric oxide GO:0071732
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
|
1 | Q9R1E0 (/IDA) |
|
Extrinsic apoptotic signaling pathway in absence of ligand GO:0097192
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
|
1 | Q9WVH4 (/IGI) |
|
Positive regulation of neuromuscular synaptic transmission GO:1900075
Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.
|
1 | O16850 (/IGI) |
|
Positive regulation of cellular response to insulin stimulus GO:1900078
Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.
|
1 | Q95V55 (/IGI) |
|
Positive regulation of defense response to bacterium GO:1900426
Any process that activates or increases the frequency, rate or extent of defense response to bacterium.
|
1 | O16850 (/IMP) |
|
Response to fluoride GO:1902617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.
|
1 | G3V7R4 (/IEP) |
|
Regulation of dauer entry GO:1905909
Any process that modulates the frequency, rate or extent of dauer entry.
|
1 | O16850 (/IGI) |
|
Positive regulation of octopamine signaling pathway GO:2000130
Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway.
|
1 | Q95V55 (/IMP) |
|
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
|
1 | Q95V55 (/IGI) |
|
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
|
1 | Q95V55 (/IMP) |
There are 20 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
20 |
A4L7N3 (/ISS)
A8MYZ6 (/ISS)
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
(10 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
20 |
A4L7N3 (/ISS)
A8MYZ6 (/ISS)
B3LYS5 (/ISS)
B3P0K6 (/ISS)
B4G4S8 (/ISS)
B4HF64 (/ISS)
B4JSC2 (/ISS)
B4KBF6 (/ISS)
B4MB78 (/ISS)
B4NFR1 (/ISS)
(10 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
16 |
A0A096MJF0 (/IDA)
A0A096MJN1 (/IDA)
A4L7N3 (/IDA)
B3G3K1 (/IDA)
D3ZBQ1 (/IDA)
D4A433 (/IDA)
F1RME6 (/IDA)
G3V7R4 (/IDA)
O16850 (/IDA)
O43524 (/IDA)
(6 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
16 |
A0A096MJF0 (/IDA)
A4L7N3 (/IDA)
B3G3K1 (/IDA)
D3ZBQ1 (/IDA)
D4A433 (/IDA)
F1NNE8 (/IDA)
F1RME6 (/IDA)
G3V7R4 (/IDA)
O16850 (/IDA)
O43524 (/IDA)
(6 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
8 | A0A096MJF0 (/IDA) A0A096MJN1 (/IDA) D3ZBQ1 (/IDA) D4A433 (/IDA) G3V7R4 (/IDA) O16850 (/IDA) O43524 (/IDA) P98177 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) Q9WVH3 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | O43524 (/TAS) P98177 (/TAS) Q12778 (/TAS) Q9R1E0 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | Q12778 (/ISS) Q66JJ0 (/ISS) Q6EUW2 (/ISS) Q810W5 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | O43524 (/TAS) P98177 (/TAS) Q12778 (/TAS) Q9R1E0 (/TAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q9R1E0 (/ISO) Q9WVH3 (/ISO) Q9WVH4 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q9R1E0 (/ISO) Q9WVH3 (/ISO) Q9WVH4 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | A0A096MJN1 (/IDA) D3ZBQ1 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9WVH3 (/ISO) Q9WVH4 (/ISO) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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1 | Q95V55 (/IC) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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1 | P98177 (/TAS) |
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Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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1 | O43524 (/IDA) |
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Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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1 | Q9WVH4 (/ISO) |
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Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
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1 | Q9WVH4 (/IDA) |
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Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
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1 | P98177 (/IDA) |
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Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
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1 | Q9WVH3 (/ISO) |