CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.300.30
Functional Family Acetyl-coenzyme A synthetase, cytoplasmic

Enzyme Information

6.2.1.1
Acetate--CoA ligase.
based on mapping to UniProt J9VFT1
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
-!- Also acts on propanoate and propenoate.

UniProtKB Entries (1)

J9VFT1
J9VFT1_CRYNH
Cryptococcus neoformans var. grubii H99
Acetyl-coenzyme A synthetase

PDB Structure

PDB 5K8F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Acetyl-CoA Synthetase in complex with ATP and Acetyl-AMP from Cryptococcus neoformans H99
Seattle Structural Genomics Center for Infectious Disease (SSGCID), SSGCID, Fox III, D., Delker, S.L., Potts, K.T., Numa, M.M., Edwards, T.E., Lorimer, D.D., Mutz, M.W., Krysan, D.J.
To Be Published