CATH Classification

Domain Context

CATH Clusters

Superfamily Chitosanase, subunit A, domain 1
Functional Family Chitosanase

Enzyme Information

3.2.1.132
Chitosanase.
based on mapping to UniProt P33673
Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan.
-!- A whole spectrum of chitosanases are now known that can hydrolyze various types of links in chitosan. -!- The only constant property is the endohydrolysis of GlcN-GlcN links, which is common to all known chitosanases. -!- One known chitosanase is limited to this link recognition, while the majority can also recognize GlcN-GlcNAc links or GlcNAc-GlcN links but not both. -!- They also do not recognize GlcNAc-GlcNAc links in partly acetylated chitosan.

UniProtKB Entries (1)

P33673
CHIS_BACCI
Bacillus circulans
Chitosanase

PDB Structure

PDB 5HWA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Understanding for the catalytic mechanism based on the substrate-bound structure of GH-46 chitosanase from Bacillus circulans MH-K1
Suzuki, M., Saito, A., Kobayashi, M., Yokoyama, T., Omiya, S., Li, J., Sugita, K., Ando, A., Miki, K., Saito, J.
to be published