CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Proto-oncogene tyrosine-protein kinase Src

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P06241
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P06241
FYN_HUMAN
Homo sapiens
Tyrosine-protein kinase Fyn

PDB Structure

PDB 4ZNX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
Camara-Artigas, A., Ortiz-Salmeron, E., Andujar-Sanchez, M., Bacarizo, J., Martin-Garcia, J.M.
Acta Crystallogr.,Sect.F