CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.340 | Nitric Oxide Synthase; Chain A, domain 1 |
|
3.90.340.10 | Nitric Oxide Synthase; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Nitric Oxide Synthase; Chain A, domain 1 |
| Functional Family | Nitric oxide synthase, inducible |
Enzyme Information
| 1.14.13.165 |
Nitric-oxide synthase (NAD(P)H).
based on mapping to UniProt O34453
2 L-arginine + 3 NAD(P)H + 4 O(2) = 2 L-citrulline + 2 nitric oxide + 3 NAD(P)(+) + 4 H(2)O.
-!- Most of the bacterial and archaeal enzymes consist of only an oxidase domain and function together with bacterial ferredoxins. -!- The enzyme from the delta-proteobacterium Sorangium cellulosum also includes a reductase domain that binds FAD, FMN and a [2Fe-2S] cluster. -!- The similar enzymes from plants and animals use only NADPH as acceptor (cf. EC 1.14.13.39).
|
UniProtKB Entries (1)
| O34453 |
NOSO_BACSU
Bacillus subtilis subsp. subtilis str. 168
Nitric oxide synthase oxygenase
|
PDB Structure
| PDB | 4UGD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase.
Biochemistry
|