CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Hypoxanthine guanine phosphoribosyltransferase

Enzyme Information

2.4.2.8
Hypoxanthine phosphoribosyltransferase.
based on mapping to UniProt Q81KC7
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- Guanine and 6-mercaptopurine can replace hypoxanthine.

UniProtKB Entries (1)

Q81KC7
Q81KC7_BACAN
Bacillus anthracis
Hypoxanthine phosphoribosyltransferase

PDB Structure

PDB 4QYI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
1.95 Angstrom resolution crystal structure of a hypoxanthine-guanine phosphoribosyltransferase (hpt-2) from Bacillus anthracis str. 'Ames Ancestor' with HEPES molecule in the active site
Halavaty, A.S., Minasov, G., Dubrovska, I., Winsor, J., Shuvalova, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
To be Published