CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.226 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
|
3.90.226.10 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
| Functional Family | Propionyl-CoA carboxylase, beta subunit |
Enzyme Information
| 6.4.1.- |
Forming carbon-carbon bonds.
based on mapping to UniProt I6YDK7
|
| 6.4.1.3 |
Propionyl-CoA carboxylase.
based on mapping to UniProt I6YDK7
ATP + propanoyl-CoA + HCO(3)(-) = ADP + phosphate + (S)-methylmalonyl- CoA.
-!- Also carboxylates butanoyl-CoA and catalyzes transcarboxylation.
|
| 2.1.3.1 |
Methylmalonyl-CoA carboxytransferase.
based on mapping to UniProt I6YDK7
(S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate.
|
UniProtKB Entries (1)
| I6YDK7 |
I6YDK7_MYCTU
Mycobacterium tuberculosis H37Rv
Methylcrotonoyl-CoA carboxylase
|
PDB Structure
| PDB | 4Q0G |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of Beta subunit of acyl-CoA carboxylase AccD1 from Mycobacterium tuberculosis
To be Published
|