CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Aspartate aminotransferase P2, mitochondrial

Enzyme Information

2.6.1.1
Aspartate transaminase.
based on mapping to UniProt Q4FX34
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
-!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. -!- This activity can be formed from EC 2.6.1.57 by controlled proteolysis.

UniProtKB Entries (1)

Q4FX34
Q4FX34_LEIMA
Leishmania major
Aspartate aminotransferase

PDB Structure

PDB 4H51
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia.
Abendroth, J., Choi, R., Wall, A., Clifton, M.C., Lukacs, C.M., Staker, B.L., Van Voorhis, W., Myler, P., Lorimer, D.D., Edwards, T.E.
Acta Crystallogr F Struct Biol Commun