CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1820
Functional Family Haloalkane dehalogenase dhaA (1-chlorohexane halidohydrolase)

Enzyme Information

3.8.1.5
Haloalkane dehalogenase.
based on mapping to UniProt P0A3G2
1-haloalkane + H(2)O = a primary alcohol + halide.
-!- Acts on a wide range of 1-haloalkanes, haloalcohols, haloalkenes and some haloaromatic compounds.

UniProtKB Entries (1)

P0A3G2
DHAA_RHORH
Rhodococcus rhodochrous
Haloalkane dehalogenase

PDB Structure

PDB 4E46
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents.
Stepankova, V., Khabiri, M., Brezovsky, J., Pavelka, A., Sykora, J., Amaro, M., Minofar, B., Prokop, Z., Hof, M., Ettrich, R., Chaloupkova, R., Damborsky, J.
Chembiochem