CATH Classification
Domain Context
CATH Clusters
| Superfamily | MurE/MurF, N-terminal domain |
| Functional Family |
Enzyme Information
| 6.3.2.10 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
based on mapping to UniProt Q9HVZ7
ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl- D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D- glutamyl-L-lysyl-D-alanyl-D-alanine.
-!- Involved with EC 6.3.2.4, EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8 and EC 6.3.2.9 in the synthesis of a cell-wall peptide. -!- Also catalyzes the reaction when the C-terminal residue of the tripeptide is meso-2,4-diaminoheptanedioate (acylated at its L-center), linking the D-Ala--D-Ala to the carboxy group of the L-center. -!- Formerly EC 6.3.2.15.
|
UniProtKB Entries (1)
| Q9HVZ7 |
Q9HVZ7_PSEAE
Pseudomonas aeruginosa PAO1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
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PDB Structure
| PDB | 4CVL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Pamurf in Complex with AMP-Pnp
To be Published
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