CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.170 |
Domain Context
CATH Clusters
| Superfamily | 3.40.630.170 |
| Functional Family |
Enzyme Information
| 2.3.1.97 |
Glycylpeptide N-tetradecanoyltransferase.
based on mapping to UniProt A5K1A2
Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.
-!- The enzyme from Saccharomyces cerevisiae is highly specific for tetradecanoyl-CoA, and for N-terminal glycine in oligopeptides containing serine in the 5-position. -!- The enzyme from mammalian heart transfers acyl groups to a specific acceptor protein of 51 kDa.
|
UniProtKB Entries (1)
| A5K1A2 |
A5K1A2_PLAVS
Plasmodium vivax Sal-1
Glycylpeptide N-tetradecanoyltransferase
|
PDB Structure
| PDB | 4CAF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Design and Synthesis of High Affinity Inhibitors of Plasmodium Falciparum and Plasmodium Vivax N-Myristoyltransferases Directed by Ligand Efficiency Dependent Lipophilicity (Lelp).
J.Med.Chem.
|