CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.160.20
Functional Family ATP-dependent RNA helicase A

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt Q08211
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q08211
DHX9_HUMAN
Homo sapiens
ATP-dependent RNA helicase A

PDB Structure

PDB 3VYX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9)
Fu, Q., Yuan, Y.A.
Nucleic Acids Res.