CATH Classification
Domain Context
CATH Clusters
| Superfamily | 3.90.1200.10 |
| Functional Family | Neomycin phosphotransferase III |
Enzyme Information
| 2.7.1.95 |
Kanamycin kinase.
based on mapping to UniProt P0A3Y5
ATP + kanamycin = ADP + kanamycin 3'-phosphate.
-!- Also acts on the antibiotics neomycin, paromomycin, neamine, paromamine, vistamycin and gentamicin A. -!- An enzyme from Pseudomonas aeruginosa also acts on butirosin.
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UniProtKB Entries (1)
| P0A3Y5 |
KKA3_ENTFL
Enterococcus faecalis
Aminoglycoside 3'-phosphotransferase
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PDB Structure
| PDB | 3Q2J |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor.
Plos One
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