CATH Domain 3m5nA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

B3TKQ3_9HEPC

Hepatitis C virus subtype 1a

Genome polyprotein

PDB Structure

PDB	3M5N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding. Romano, K.P., Ali, A., Royer, W.E., Schiffer, C.A. Proc.Natl.Acad.Sci.USA