CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | Genome polyprotein |
Enzyme Information
UniProtKB Entries (2)
| Q9WPH5 |
Q9WPH5_9HEPC
Hepatitis C virus subtype 1b
Genome polyprotein
|
| A8DG50 |
A8DG50_9HEPC
Hepatitis C virus subtype 1a
Genome polyprotein
|
PDB Structure
| PDB | 3M5M |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding.
Proc.Natl.Acad.Sci.USA
|