CATH Classification

Domain Context

CATH Clusters

Superfamily TolB, C-terminal domain
Functional Family Senescence marker protein-30 (SMP-30)

Enzyme Information

3.1.8.2
Diisopropyl-fluorophosphatase.
based on mapping to UniProt Q7SIG4
Diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + fluoride.
-!- Acts on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases). -!- Inhibited by chelating agents. -!- Related to EC 3.1.8.1. -!- Formerly EC 3.8.2.1.

UniProtKB Entries (1)

Q7SIG4
DFPA_LOLVU
Loligo vulgaris
Diisopropyl-fluorophosphatase

PDB Structure

PDB 3KGG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): perdeuteration of proteins for neutron diffraction.
Blum, M.M., Tomanicek, S.J., John, H., Hanson, B.L., Ruterjans, H., Schoenborn, B.P., Langan, P., Chen, J.C.
Acta Crystallogr.,Sect.F