CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | Alpha/Beta hydrolase fold, catalytic domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.1820 |
| Functional Family | Lysosomal Pro-X carboxypeptidase, putative |
Enzyme Information
| 3.4.14.2 |
Dipeptidyl-peptidase II.
based on mapping to UniProt Q9UHL4
Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides.
-!- A lysosomal serine-type peptidase maximally active at acidic pH. -!- Cleaves Lys-Ala-naphthylamide. -!- Belongs to peptidase family S28.
|
UniProtKB Entries (1)
| Q9UHL4 |
DPP2_HUMAN
Homo sapiens
Dipeptidyl peptidase 2
|
PDB Structure
| PDB | 3JYH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Human dipeptidyl peptidase DPP7
To be Published
|