CATH Classification
Domain Context
CATH Clusters
| Superfamily | Ubiquinol cytochrome reductase, transmembrane domain |
| Functional Family | Cytochrome b-c1 complex subunit Rieske, mitochondrial |
Enzyme Information
| 1.10.2.2 |
Quinol--cytochrome-c reductase.
based on mapping to UniProt Q5ZLR5
Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H(+).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and C(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3).
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UniProtKB Entries (1)
| D0VX31 |
D0VX31_CHICK
Gallus gallus
Mitochondrial ubiquinol-cytochrome-c reductase complex core protein i
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PDB Structure
| PDB | 3H1L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc(1) complex.
Biochim.Biophys.Acta
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