CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family

Enzyme Information

2.6.1.62
Adenosylmethionine--8-amino-7-oxononanoate transaminase.
based on mapping to UniProt P9WQ81
S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4- methylthio-2-oxobutanoate + 7,8-diaminononanoate.
-!- S-adenosylhomocysteine can also act as donor.

UniProtKB Entries (1)

P9WQ81
BIOA_MYCTU
Mycobacterium tuberculosis H37Rv
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

PDB Structure

PDB 3BV0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase .
Dey, S., Lane, J.M., Lee, R.E., Rubin, E.J., Sacchettini, J.C.
Biochemistry