CATH Classification

Domain Context

CATH Clusters

Superfamily Golgi alpha-mannosidase II
Functional Family Alpha mannosidase II, isoform B

Enzyme Information

3.2.1.114
Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase.
based on mapping to UniProt Q24451
Hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).
-!- Involved in the synthesis of glycoproteins.

UniProtKB Entries (1)

Q24451
MAN2_DROME
Drosophila melanogaster
Alpha-mannosidase 2

PDB Structure

PDB 3BUP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant.
Zhong, W., Kuntz, D.A., Ember, B., Singh, H., Moremen, K.W., Rose, D.R., Boons, G.J.
J.Am.Chem.Soc.