CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.620 | HUPs |
Domain Context
CATH Clusters
| Superfamily | HUPs |
| Functional Family | FAD synthetase, putative (AFU_orthologue AFUA_6G11040) |
Enzyme Information
| 2.7.7.2 |
FAD synthetase.
based on mapping to UniProt P38913
ATP + FMN = diphosphate + FAD.
-!- Highly specific for ATP as phosphate donor. -!- The cofactors FMN and FAD participate in numerous processes in all organisms, including mitochondrial electron transport, photosynthesis, fatty-acid oxidation, and metabolism of vitamin B6, vitamin B12 and folates. -!- While monofunctional FAD synthetase is found in eukaryotes and in some prokaryotes, most prokaryotes have a bifunctional enzyme that exhibits both this activity and that of EC 2.7.1.26.
|
UniProtKB Entries (1)
| P38913 |
FAD1_YEAST
Saccharomyces cerevisiae S288C
FAD synthase
|
PDB Structure
| PDB | 2WSI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Yeast Fad Synthetase (Fad1) in Complex with Fad.
J.Mol.Biol.
|