CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate carbamoyltransferase regulatory subunit, N-terminal domain
Functional Family Aspartate carbamoyltransferase regulatory chain

Enzyme Information

2.1.3.2
Aspartate carbamoyltransferase.
based on mapping to UniProt P0A7F3
Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.

UniProtKB Entries (1)

P0A7F3
PYRI_ECOLI
Escherichia coli K-12
Aspartate carbamoyltransferase regulatory chain

PDB Structure

PDB 2QG9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Comparison of two T-state structures of regulatory-chain mutants of Escherichia coli aspartate transcarbamoylase suggests that His20 and Asp19 modulate the response to heterotropic effectors.
Stec, B., Williams, M.K., Stieglitz, K.A., Kantrowitz, E.R.
Acta Crystallogr.,Sect.D