CATH Classification

Domain Context

CATH Clusters

Superfamily Galactose-binding domain-like
Functional Family Hyaluronoglucosaminidase

Enzyme Information

3.2.1.35
Hyaluronoglucosaminidase.
based on mapping to UniProt A0A0H2YRL1
Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
-!- Also hydrolyzes 1,4-beta-D-glycosidic linkages between N-acetyl- galactosamine or N-acetylgalactosamine sulfate and glucuronic acid in chondroitin, chondroitin 4- and 6-sulfates, and dermatan. -!- Formerly EC 3.2.1.34.

UniProtKB Entries (1)

A0A0H2YRL1
A0A0H2YRL1_CLOP1
Clostridium perfringens ATCC 13124
Hyaluronoglucosaminidase

PDB Structure

PDB 2LS6
External Links
Method SOLUTION NMR
Organism
Primary Citation
An unusual mode of galactose recognition by a family 32 carbohydrate-binding module.
Grondin, J.M., Chitayat, S., Ficko-Blean, E., Houliston, S., Arrowsmith, C.H., Boraston, A.B., Smith, S.P.
J.Mol.Biol.