CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.100 |
Domain Context
CATH Clusters
| Superfamily | 3.30.70.100 |
| Functional Family | Putative cadmium/zinc-transporting ATPase HMA4 |
Enzyme Information
| 3.6.3.3 |
Cadmium-exporting ATPase.
based on mapping to UniProt O64474
ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out).
-!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
|
| 3.6.3.5 |
Zinc-exporting ATPase.
based on mapping to UniProt O64474
ATP + H(2)O + Zn(2+)(In) = ADP + phosphate + Zn(2+)(Out).
-!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme also exports Cd(2+) and Co(2+).
|
UniProtKB Entries (1)
| O64474 |
HMA4_ARATH
Arabidopsis thaliana
Putative cadmium/zinc-transporting ATPase HMA4
|
PDB Structure
| PDB | 2KKH |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Metal binding affinities of Arabidopsis zinc and copper transporters: selectivities match the relative, but not the absolute, affinities of their amino-terminal domains
Biochemistry
|
