CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.7700 | PurE domain |
Domain Context
CATH Clusters
| Superfamily | PurE domain |
| Functional Family | Probable N5-carboxyaminoimidazole ribonucleotide mutase |
Enzyme Information
| 5.4.99.18 |
5-(carboxyamino)imidazole ribonucleotide mutase.
based on mapping to UniProt Q2QJL3
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxylate.
-!- In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates. -!- In the absence of EC 6.3.2.6, the reaction is reversible. -!- The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation.
|
UniProtKB Entries (1)
| Q2QJL3 |
Q2QJL3_ACEAC
Acetobacter aceti
N5-carboxyaminoimidazole ribonucleotide mutase
|
PDB Structure
| PDB | 2FWP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Biochemical and Structural Studies of N(5)-Carboxyaminoimidazole Ribonucleotide Mutase from the Acidophilic Bacterium Acetobacter aceti.
Biochemistry
|