CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.11540
Functional Family

Enzyme Information

1.6.5.11
NADH dehydrogenase (quinone).
based on mapping to UniProt Q56222
NADH + a quinone = NAD(+) + a quinol.
-!- Menaquinone or other quinones can act as acceptor. -!- Inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. -!- Formerly EC 1.6.99.5.

UniProtKB Entries (1)

Q56222
NQO1_THET8
Thermus thermophilus HB8
NADH-quinone oxidoreductase subunit 1

PDB Structure

PDB 2FUG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
Sazanov, L.A., Hinchliffe, P.
Science