CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.330
Functional Family Alkylated DNA repair protein alkB homolog 8

Enzyme Information

2.1.1.229
tRNA (carboxymethyluridine(34)-5-O)-methyltransferase.
based on mapping to UniProt Q96BT7
S-adenosyl-L-methionine + carboxymethyluridine(34) in tRNA = S-adenosyl- L-homocysteine + 5-(2-methoxy-2-oxoethyl)uridine(34) in tRNA.
-!- The enzyme catalyzes the posttranslational modification of uridine residues at the wobble position 34 of the anticodon loop of tRNA.
1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q96BT7

UniProtKB Entries (1)

Q96BT7
ALKB8_HUMAN
Homo sapiens
Alkylated DNA repair protein alkB homolog 8

PDB Structure

PDB 2CQ2
External Links
Method SOLUTION NMR
Organism
Primary Citation
solution structure of RNA binding domain in Hypothetical protein LOC91801
Tsuda, K., Muto, Y., Inoue, M., Kigawa, T., Terada, T., Shirouzu, M., Yokoyama, S.
To be Published