CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.1110 | Calcium-transporting ATPase, cytoplasmic domain N | |
3.40.1110.10 | Calcium-transporting ATPase, cytoplasmic domain N |
Domain Context
CATH Clusters
Superfamily | Calcium-transporting ATPase, cytoplasmic domain N |
Functional Family | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type |
Enzyme Information
3.6.3.8 |
Calcium-transporting ATPase.
based on mapping to UniProt P04191
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
-!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme family comprises three types of Ca(2+)-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in Saccharomyces cerevisiae. -!- The first and third transport one ion per ATP hydrolyzed, whereas the second transports two ions. -!- Formerly EC 3.6.1.38.
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UniProtKB Entries (1)
P04191 |
AT2A1_RABIT
Oryctolagus cuniculus
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
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PDB Structure
PDB | 2C88 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Modulatory and Catalytic Modes of ATP Binding by the Calcium Pump
Embo J.
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