CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Adenylate kinase isoenzyme 1

Enzyme Information

2.7.4.3
Adenylate kinase.
based on mapping to UniProt Q9Y6K8
ATP + AMP = 2 ADP.
-!- Inorganic triphosphate can also act as donor.
2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt Q9Y6K8
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

Q9Y6K8
KAD5_HUMAN
Homo sapiens
Adenylate kinase isoenzyme 5

PDB Structure

PDB 2BWJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Adenylate Kinase 5
Filippakopoulos, P., Bunkoczi, G., Jansson, A., Longman, E., Knapp, S.
To be Published