CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
Superfamily | Vaccinia Virus protein VP39 |
Functional Family | Putative spermidine synthase 1 |
Enzyme Information
2.5.1.16 |
Spermidine synthase.
based on mapping to UniProt G5EFG3
S-adenosyl 3-(methylthio)propylamine + putrescine = 5'-S-methyl- 5'-thioadenosine + spermidine.
-!- The enzymes from the plant Glycine max and from mammalia are highly specific for putrescine as the amine acceptor. -!- The enzymes from the bacteria Escherichia coli and Thermotoga maritima prefer putrescine but are more tolerant toward other amine acceptors, such as spermidine and cadaverine. -!- Cf. EC 2.5.1.22 and EC 2.5.1.23.
|
UniProtKB Entries (1)
G5EFG3 |
G5EFG3_CAEEL
Caenorhabditis elegans
SPermiDine Synthase
|
PDB Structure
PDB | 2B2C |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Cloning, expression, characterisation and three-dimensional structure determination of Caenorhabditis elegans spermidine synthase
FEBS LETT.
|