CATH Classification

Domain Context

CATH Clusters

Superfamily Chorismate synthase AroC
Functional Family Chorismate synthase 2, chloroplastic

Enzyme Information

4.2.3.5
Chorismate synthase.
based on mapping to UniProt P56122
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.
-!- The reaction goes via a radical mechanism that involves reduced FMN and its semiquinone (FMNH.). -!- Shikimate is numbered so that the double-bond is between C-1 and C-2, but some earlier papers numbered the ring in the reverse direction. -!- Formerly EC 4.6.1.4.

UniProtKB Entries (1)

P56122
AROC_HELPY
Helicobacter pylori 26695
Chorismate synthase

PDB Structure

PDB 1UM0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of chorismate synthase: a novel FMN-binding protein fold and functional insights
Ahn, H.J., Yoon, H.J., Lee, B., Suh, S.W.
J.Mol.Biol.