CATH Classification

Domain Context

CATH Clusters

Superfamily Dihydrodipicolinate Reductase; domain 2
Functional Family Cytosolic glyceraldehyde-3-phosphate dehydrogenase GAPDH

Enzyme Information

2.6.99.-
Transferring other nitrogenous groups.
based on mapping to UniProt P04406
1.2.1.12
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
based on mapping to UniProt P04406
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
-!- Also acts very slowly on D-glyceraldehyde and some other aldehydes. -!- Thiols can replace phosphate.

UniProtKB Entries (1)

P04406
G3P_HUMAN
Homo sapiens
Glyceraldehyde-3-phosphate dehydrogenase

PDB Structure

PDB 1U8F
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
High-resolution structure of human D-glyceraldehyde-3-phosphate dehydrogenase.
Jenkins, J.L., Tanner, J.J.
Acta Crystallogr.,Sect.D