CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
Superfamily | NAD(P)-binding Rossmann-like Domain |
Functional Family |
Enzyme Information
1.1.1.14 |
L-iditol 2-dehydrogenase.
based on mapping to UniProt Q00796
L-iditol + NAD(+) = L-sorbose + NADH.
-!- This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals. -!- It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol. -!- Enzymes from different organisms or tissues display different substrate specificity. -!- The enzyme is specific to NAD(+) and can not use NADP(+).
|
UniProtKB Entries (1)
Q00796 |
DHSO_HUMAN
Homo sapiens
Sorbitol dehydrogenase
|
PDB Structure
PDB | 1PL8 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.
Structure
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