CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Hemocyte protein-glutamine gamma-glutamyltransferase, putative

Enzyme Information

2.3.2.13
Protein-glutamine gamma-glutamyltransferase.
based on mapping to UniProt Q08188
Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).
-!- The gamma-carboxymide groups of peptide-bound glutamine residues act as acyl donors, and the 6-amino-groups of protein- and peptide-bound lysine residues act as acceptors, to give intra- and inter-molecular N(6)-(5-glutamyl)lysine crosslinks.

UniProtKB Entries (1)

Q08188
TGM3_HUMAN
Homo sapiens
Protein-glutamine gamma-glutamyltransferase E

PDB Structure

PDB 1NUF
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
Roles of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme
Ahvazi, B., Boeshans, K.M., Idler, W., Baxa, U., Steinert, P.M.
J.Biol.Chem.