CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.980
Functional Family Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)

Enzyme Information

1.13.12.7
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing).
based on mapping to UniProt P08659
Photinus luciferin + O(2) + ATP = oxidized Photinus luciferin + CO(2) + AMP + diphosphate + light.
-!- Photinus (firefly) is a bioluminescent insect. -!- The first step in the reaction is the formation of an acid anhydride between the carboxylic group and AMP, with the release of diphosphate. -!- The enzyme may be assayed by measurement of light emission.

UniProtKB Entries (1)

P08659
LUCI_PHOPY
Photinus pyralis
Luciferin 4-monooxygenase

PDB Structure

PDB 1LCI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes.
Conti, E., Franks, N.P., Brick, P.
Structure