CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10090 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.10090 |
| Functional Family | Uroporphyrinogen III synthase, isoform CRA_b |
Enzyme Information
| 4.2.1.75 |
Uroporphyrinogen-III synthase.
based on mapping to UniProt P10746
Hydroxymethylbilane = uroporphyrinogen III + H(2)O.
-!- In the presence of EC 2.5.1.61, forms uroporphyrinogen III from porphobilinogen.
|
UniProtKB Entries (1)
| P10746 |
HEM4_HUMAN
Homo sapiens
Uroporphyrinogen-III synthase
|
PDB Structure
| PDB | 1JR2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of human uroporphyrinogen III synthase.
EMBO J.
|