CATH Classification

Domain Context

CATH Clusters

Superfamily Integrase, C-terminal domain superfamily, retroviral
Functional Family Pol polyprotein

Enzyme Information

2.7.7.-
Nucleotidyltransferases.
based on mapping to UniProt P04586
3.1.-.-
Acting on ester bonds.
based on mapping to UniProt P04586

UniProtKB Entries (1)

P04586
POL_HV1Z6
Human immunodeficiency virus type 1 (ZAIRE 6 ISOLATE)
Gag-Pol polyprotein

PDB Structure

PDB 1IHW
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure of the DNA binding domain of HIV-1 integrase.
Lodi, P.J., Ernst, J.A., Kuszewski, J., Hickman, A.B., Engelman, A., Craigie, R., Clore, G.M., Gronenborn, A.M.
Biochemistry