CATH Classification

Domain Context

CATH Clusters

Superfamily Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
Functional Family Probable isoleucine--tRNA ligase, mitochondrial

Enzyme Information

6.1.1.5
Isoleucine--tRNA ligase.
based on mapping to UniProt P41972
ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile).

UniProtKB Entries (1)

P41972
SYI1_STAAU
Staphylococcus aureus
Isoleucine--tRNA ligase

PDB Structure

PDB 1FFY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin.
Silvian, L.F., Wang, J., Steitz, T.A.
Science