CATH Classification

Domain Context

CATH Clusters

Superfamily Enolase-like C-terminal domain
Functional Family Enolase 2, putative, expressed

Enzyme Information

4.2.1.11
Phosphopyruvate hydratase.
based on mapping to UniProt P00924
2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.
-!- Also acts on 3-phospho-D-erythronate.

UniProtKB Entries (1)

P00924
ENO1_YEAST
Saccharomyces cerevisiae S288C
Enolase 1

PDB Structure

PDB 1EBG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Chelation of serine 39 to Mg2+ latches a gate at the active site of enolase: structure of the bis(Mg2+) complex of yeast enolase and the intermediate analog phosphonoacetohydroxamate at 2.1-A resolution.
Wedekind, J.E., Poyner, R.R., Reed, G.H., Rayment, I.
Biochemistry