CATH Classification

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family Thioredoxin reductase

Enzyme Information

1.8.1.9
Thioredoxin-disulfide reductase.
based on mapping to UniProt P0A9P4
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.

UniProtKB Entries (1)

P0A9P4
TRXB_ECOLI
Escherichia coli K-12
Thioredoxin reductase

PDB Structure

PDB 1CL0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of reduced thioredoxin reductase from Escherichia coli: structural flexibility in the isoalloxazine ring of the flavin adenine dinucleotide cofactor.
Lennon, B.W., Williams Jr., C.H., Ludwig, M.L.
Protein Sci.