CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Son of sevenless 2

Enzyme Information

UniProtKB Entries (1)

Q07889
SOS1_HUMAN
Homo sapiens
Son of sevenless homolog 1

PDB Structure

PDB 1AWE
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
Zheng, J., Chen, R.H., Corblan-Garcia, S., Cahill, S.M., Bar-Sagi, D., Cowburn, D.
J.Biol.Chem.