CATH Classification

Domain Context

CATH Clusters

Superfamily Inorganic pyrophosphatase
Functional Family Inorganic pyrophosphatase 2, mitochondrial

Enzyme Information

3.6.1.1
Inorganic diphosphatase.
based on mapping to UniProt P00817
Diphosphate + H(2)O = 2 phosphate.
-!- Specificity varies with the source and with the activating metal ion. -!- The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9.

UniProtKB Entries (1)

P00817
IPYR_YEAST
Saccharomyces cerevisiae S288C
Inorganic pyrophosphatase

PDB Structure

PDB 117E
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications.
Tuominen, V., Heikinheimo, P., Kajander, T., Torkkel, T., Hyytia, T., Kapyla, J., Lahti, R., Cooperman, B.S., Goldman, A.
J.Mol.Biol.