The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Replicase polyprotein, nucleic acid-binding domain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Replicase polyprotein, nucleic acid-binding domain

Structural domains comprising this superfamily share the structure of the nucleic acid binding domain (NAB/NAR), mainly found in Orf1a polyproteins of the severe acute respiratory syndrome coronavirus PMID:12730500. This domain presents a group of residues that form a positively charged patch on the protein surface which give rise to the nucleic acid binding site PMID:19828617.

GO Diversity

Unique GO annotations
5 Unique GO terms

EC Diversity

Unique EC annotations
5 Unique EC terms

Species Diversity

Unique species annotations
82 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 3
Unique EC: 5
Unique GO: 5
Unique Species: 82